Frontline Plus for Cats (Green, 6-pack) is a topical spot-on flea and tick treatment for cats and kittens from 8 weeks of age. Each pipette delivers a month's protection, so the 6-pack covers half a year of monthly dosing. It's applied to the skin at the base of the neck where the cat can't lick it off.

The formulation combines fipronil and (S)-methoprene. Fipronil kills adult fleas and biting lice on the cat, typically within 24 hours, while (S)-methoprene targets flea eggs and larvae in the surrounding environment. Together they break the flea life cycle rather than just clearing the visible adults, which is what makes it effective against re-infestation from bedding, carpets, and other pets in the household. It's waterproof once dry, so bathing and normal grooming don't compromise the treatment.

Cat owners tend to stick with Frontline Plus because it's a well-established, vet-familiar option that handles both the cat and the household side of a flea problem. The 6-pack format is the one most people default to for straightforward monthly dosing without having to reorder every month.